![]() They said that the two couldn’t possibly be related, that he needed to keep taking the medication, and that he should stay in the study,” says Golomb. ![]() ![]() Are digital drugs the future of medication?Īlarmed, the couple turned to the study’s organisers.“He was like, ‘Wow, it really seems that these problems started when I enrolled in this study’,” says Beatrice Golomb, who leads a research group at the University of California, San Diego. Then one day, Patient Five had an epiphany. She became increasingly fearful for her own safety. Afterwards, she’d leave him alone to watch TV and calm down. Even as a passenger, his outbursts often forced his wife to abandon their journeys and turn back. Out of fear of what might happen, Patient Five stopped driving. During one memorable episode, he warned his family to keep away, lest he put them in hospital. A previously reasonable man, he became explosively angry and – out of nowhere – developed a tendency for road rage. So far, so normal.īut soon after he began the treatment, his wife began to notice a sinister transformation. He had diabetes, and he had signed up for a study to see if taking a “statin” – a kind of cholesterol-lowering drug – might help. “Patient Five” was in his late 50s when a trip to the doctors changed his life. To mark the end of a turbulent year, we are bringing back some of our favourite stories for BBC Future’s “Best of 2020” collection.
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